MAGED4B

Melanoma-associated antigen D4 is a protein that in humans is encoded by the MAGED4B gene.[3]

MAGED4B
Identifiers
AliasesMAGED4B, MAGE family member D4B
External IDsOMIM: 300765 HomoloGene: 52232 GeneCards: MAGED4B
Gene location (Human)
Chr.X chromosome (human)[1]
BandXp11.22Start52,061,827 bp[1]
End52,069,248 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

81557

n/a

Ensembl

ENSG00000187243

n/a

UniProt

Q96JG8

n/a

RefSeq (mRNA)

NM_001242362
NM_030801
NM_177535
NM_177537

n/a

RefSeq (protein)

NP_001092270
NP_001258990
NP_001258991
NP_001258992

n/a

Location (UCSC)Chr X: 52.06 – 52.07 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

This gene is related to members of the MAGED gene family, in terms of the sequence similarity and the chromosome location. This gene is expressed only in brain and ovary among normal tissues, and two transcript variants of this gene are specifically expressed in glioma cells among cancer cells. This gene and the other MAGED genes are clustered on chromosome Xp11. Multiple alternatively spliced transcript variants have been found for this gene, however, the full length nature of some variants has not been defined.[3]

References

  1. GRCh38: Ensembl release 89: ENSG00000187243 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "MAGED4B MAGE family member D4B [Homo sapiens (human)]". National Center for Biotechnology Information. Retrieved 28 September 2020.

Further reading

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