MARCH6

E3 ubiquitin-protein ligase MARCH6 is an enzyme that in humans is encoded by the MARCH6 gene.[5][6]

MARCHF6
Identifiers
AliasesMARCHF6, DOA10, MARCH-VI, RNF176, TEB4, membrane associated ring-CH-type finger 6, MARCH6, FAME3
External IDsOMIM: 613297 MGI: 2442773 HomoloGene: 4301 GeneCards: MARCHF6
Gene location (Human)
Chr.Chromosome 5 (human)[1]
Band5p15.2Start10,353,695 bp[1]
End10,440,388 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

10299

223455

Ensembl

ENSG00000145495

ENSMUSG00000039100

UniProt

O60337

Q6ZQ89

RefSeq (mRNA)

NM_001270660
NM_001270661
NM_005885

NM_172606

RefSeq (protein)

NP_001257589
NP_001257590
NP_005876

NP_766194

Location (UCSC)Chr 5: 10.35 – 10.44 MbChr 15: 31.46 – 31.53 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Gene name error in Excel

Like the other MARCH and septin genes, care must be exercised when analyzing genetic data containing the MARCH6 gene in Microsoft Excel.[7] This is due to Excel's autocorrect feature treating the text "MARCH6" as a date and converting it to a standard date format. The original text cannot be recovered as a result of the conversion. A 2016 study found up to 19.6% of all papers in selected journals to be affected by the gene name error.[8] The issue can be prevented by using an alias name (such as MARCHF6), prepending with an apostrophe ('), or preformatting the cell as text.

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000145495 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000039100 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Fruh K (Jan 2004). "Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins". J Virol. 78 (3): 1109–20. doi:10.1128/JVI.78.3.1109-1120.2004. PMC 321412. PMID 14722266.
  6. "Entrez Gene: MARCH6 membrane-associated ring finger (C3HC4) 6".
  7. Zeeberg BR, Riss J, Kane DW, Bussey KJ, Uchio E, Linehan WM, et al. (June 2004). "Mistaken identifiers: gene name errors can be introduced inadvertently when using Excel in bioinformatics". BMC Bioinformatics. 5 (1): 80. doi:10.1186/1471-2105-5-80. PMC 459209. PMID 15214961.
  8. Ziemann M, Eren Y, El-Osta A (August 2016). "Gene name errors are widespread in the scientific literature". Genome Biology. 17 (1): 177. doi:10.1186/s13059-016-1044-7. PMC 4994289. PMID 27552985.

Further reading


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