MAZ (gene)

Myc-associated zinc finger protein is a protein that in humans is encoded by the MAZ gene.[5][6][7]

MAZ
Identifiers
AliasesMAZ, PUR1, Pur-1, SAF-1, SAF-2, SAF-3, ZF87, ZNF801, Zif87, MYC associated zinc finger protein
External IDsOMIM: 600999 MGI: 1338823 HomoloGene: 106451 GeneCards: MAZ
Gene location (Human)
Chr.Chromosome 16 (human)[1]
Band16p11.2Start29,806,106 bp[1]
End29,811,164 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

4150

17188

Ensembl

ENSG00000103495

ENSMUSG00000030678

UniProt

P56270

P56671

RefSeq (mRNA)

NM_001042539
NM_001276275
NM_001276276
NM_002383

NM_010772
NM_001372521
NM_001372522
NM_001372523

RefSeq (protein)

NP_001036004
NP_001263204
NP_001263205
NP_002374

n/a

Location (UCSC)Chr 16: 29.81 – 29.81 MbChr 7: 127.02 – 127.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

MAZ (gene) has been shown to interact with BPTF[8] and Deleted in Colorectal Cancer.[9]

References

  1. GRCh38: Ensembl release 89: ENSG00000103495 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000030678 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Pyrc JJ, Moberg KH, Hall DJ (May 1992). "Isolation of a novel cDNA encoding a zinc-finger protein that binds to two sites within the c-myc promoter". Biochemistry. 31 (16): 4102–4110. doi:10.1021/bi00131a029. PMID 1567856.
  6. Bossone SA, Asselin C, Patel AJ, Marcu KB (September 1992). "MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination". Proc Natl Acad Sci U S A. 89 (16): 7452–7456. doi:10.1073/pnas.89.16.7452. PMC 49728. PMID 1502157.
  7. "Entrez Gene: MAZ MYC-associated zinc finger protein (purine-binding transcription factor)".
  8. Jordan-Sciutto KL, Dragich JM, Caltagarone J, Hall DJ, Bowser R (March 2000). "Fetal Alz-50 clone 1 (FAC1) protein interacts with the Myc-associated zinc finger protein (ZF87/MAZ) and alters its transcriptional activity". Biochemistry. 39 (12): 3206–3215. doi:10.1021/bi992211q. PMC 3667205. PMID 10727212.
  9. Ugai H, Li HO, Komatsu M, Tsutsui H, Song J, Shiga T, Fearon E, Murata T, Yokoyama KK (September 2001). "Interaction of Myc-associated zinc finger protein with DCC, the product of a tumor-suppressor gene, during the neural differentiation of P19 EC cells". Biochem. Biophys. Res. Commun. 286 (5): 1087–1097. doi:10.1006/bbrc.2001.5469. PMID 11527412.

Further reading

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