MED25

Mediator of RNA polymerase II transcription subunit 25 is an enzyme that in humans is encoded by the MED25 gene.[5][6][7]

MED25
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMED25, ACID1, ARC92, CMT2B2, P78, PTOV2, BVSYS, TCBAP0758, mediator complex subunit 25
External IDsOMIM: 610197 MGI: 1922863 HomoloGene: 12614 GeneCards: MED25
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19q13.33Start49,818,279 bp[1]
End49,840,383 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

81857

75613

Ensembl

ENSG00000104973

ENSMUSG00000002968

UniProt

Q71SY5

Q8VCB2

RefSeq (mRNA)

NM_030973
NM_001378355

NM_029365
NM_001331206
NM_001331207
NM_001331208

RefSeq (protein)

NP_112235
NP_001365284

NP_001318135
NP_001318136
NP_001318137
NP_083641

Location (UCSC)Chr 19: 49.82 – 49.84 MbChr 7: 44.88 – 44.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

MED25 has been shown to interact with MED4.[8]

References

  1. GRCh38: Ensembl release 89: ENSG00000104973 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000002968 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Apr 1997). "Large-scale concatenation cDNA sequencing". Genome Research. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
  6. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  7. "Entrez Gene: MED25 mediator of RNA polymerase II transcription, subunit 25 homolog (S. cerevisiae)".
  8. Tomomori-Sato C, Sato S, Parmely TJ, Banks CA, Sorokina I, Florens L, Zybailov B, Washburn MP, Brower CS, Conaway RC, Conaway JW (Feb 2004). "A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2". The Journal of Biological Chemistry. 279 (7): 5846–51. doi:10.1074/jbc.M312523200. PMID 14638676.

Further reading


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