MLLT10

Protein AF-10 is a protein that in humans is encoded by the MLLT10 gene.[5][6]

MLLT10
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMLLT10, AF10, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10, histone lysine methyltransferase DOT1L cofactor
External IDsOMIM: 602409 MGI: 1329038 HomoloGene: 20973 GeneCards: MLLT10
Gene location (Human)
Chr.Chromosome 10 (human)[1]
Band10p12.31Start21,524,675 bp[1]
End21,743,630 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

8028

17354

Ensembl

ENSG00000078403

ENSMUSG00000026743

UniProt

P55197

O54826

RefSeq (mRNA)

NM_001252560
NM_001252561
NM_010804

RefSeq (protein)

NP_001239489
NP_001239490
NP_034934

Location (UCSC)Chr 10: 21.52 – 21.74 MbChr 2: 18.06 – 18.21 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

MLLT10 has been shown to interact with SS18.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000078403 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000026743 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Chaplin T, Ayton P, Bernard OA, Saha V, Della Valle V, Hillion J, Gregorini A, Lillington D, Berger R, Young BD (Apr 1995). "A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia". Blood. 85 (6): 1435–41. doi:10.1182/blood.V85.6.1435.bloodjournal8561435. PMID 7888665.
  6. "Entrez Gene: MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10".
  7. de Bruijn DR, dos Santos NR, Thijssen J, Balemans M, Debernardi S, Linder B, Young BD, Geurts van Kessel A (May 2001). "The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10". Oncogene. 20 (25): 3281–9. doi:10.1038/sj.onc.1204419. PMID 11423977.

Further reading


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