MTSS1

Metastasis suppressor protein 1 is a protein that in humans is encoded by the MTSS1 gene.[5][6][7] True to its name, it codes for a metastasis suppressor.

MTSS1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMTSS1, MIM, MIMA, MIMB, metastasis suppressor 1, I-BAR domain containing, MTSS I-BAR domain containing 1
External IDsOMIM: 608486 MGI: 2384818 HomoloGene: 8841 GeneCards: MTSS1
Gene location (Human)
Chr.Chromosome 8 (human)[1]
Band8q24.13Start124,550,790 bp[1]
End124,728,429 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9788

211401

Ensembl

ENSG00000170873

ENSMUSG00000022353

UniProt

O43312

Q8R1S4

RefSeq (mRNA)

NM_001146180
NM_144800

RefSeq (protein)

NP_001139652
NP_659049

Location (UCSC)Chr 8: 124.55 – 124.73 MbChr 15: 58.94 – 59.08 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References

  1. GRCh38: Ensembl release 89: ENSG00000170873 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000022353 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Mattila PK, Salminen M, Yamashiro T, Lappalainen P (Mar 2003). "Mouse MIM, a tissue-specific regulator of cytoskeletal dynamics, interacts with ATP-actin monomers through its C-terminal WH2 domain". J Biol Chem. 278 (10): 8452–9. doi:10.1074/jbc.M212113200. PMID 12482861.
  6. Lee YG, Macoska JA, Korenchuk S, Pienta KJ (Jun 2002). "MIM, a Potential Metastasis Suppressor Gene in Bladder Cancer". Neoplasia. 4 (4): 291–4. doi:10.1038/sj.neo.7900231. PMC 1531703. PMID 12082544.
  7. "Entrez Gene: MTSS1 metastasis suppressor 1".

Further reading


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