MYO1E

Myosin-Ie (Myo1e) is a protein that in humans is encoded by the MYO1E gene.[5][6]

MYO1E
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMYO1E, FSGS6, HuncM-IC, MYO1C, myosin IE
External IDsOMIM: 601479 MGI: 106621 HomoloGene: 55864 GeneCards: MYO1E
Gene location (Human)
Chr.Chromosome 15 (human)[1]
Band15q22.2Start59,132,434 bp[1]
End59,372,871 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

4643

71602

Ensembl

ENSG00000157483

ENSMUSG00000032220

UniProt

Q12965

E9Q634

RefSeq (mRNA)

NM_004998

NM_181072

RefSeq (protein)

NP_004989

NP_851417

Location (UCSC)Chr 15: 59.13 – 59.37 MbChr 9: 70.21 – 70.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Myosin-Ie is a long tailed myosin. It contains an N-terminal motor domain, an IQ motif, a TH1 domain containing a plecstrin homology (PH) domain, a proline rich TH2 domain, and an SH3 domain. [7]


References

  1. GRCh38: Ensembl release 89: ENSG00000157483 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000032220 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, et al. (September 1996). "Mapping of unconventional myosins in mouse and human". Genomics. 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266.
  6. "Entrez Gene: MYO1E myosin IE".
  7. McConnell RE, Tyska MJ (July 2010). "Leveraging the membrane - cytoskeleton interface with myosin-1". Trends in Cell Biology. 20 (7): 418–26. doi:10.1016/j.tcb.2010.04.004. PMC 2897960. PMID 20471271.

Further reading

  • Overview of all the structural information available in the PDB for UniProt: E9Q634 (Mouse Unconventional myosin-Ie) at the PDBe-KB.
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