Metanx

Metanx
Combination of
L-methylfolate	vitamin
Pyridoxal 5'-phosphate	vitamin
Methylcobalamin	vitamin
Clinical data
ATC code	A11EA (WHO) ;
Identifiers
ChemSpider	none;
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Metanx is a prescription medical food made by Alfasigma that contains L-methylfolate (as Metafolin, a calcium salt of vitamin B₉), methylcobalamin (vitamin B₁₂) and pyridoxal 5'-phosphate (vitamin B₆). It is a vitamin B supplement. Metanx is indicated for the dietary management of peripheral neuropathy (i.e. DPN).[1]

Ingredients

Metanx contains the following active ingredients (per capsule):

Folate
L-methylfolate (Metafolin): 3 mg
Pyridoxal 5'-phosphate: 35 mg
Methylcobalamin: 2 mg[2]

Indication and usage

Metanx is used for treating:

Painful diabetic neuropathy,[3]
Diabetic foot ulcers,[2]
Endothelial dysfunction associated with diabetic peripheral neuropathy,[2]
Hyperhomocysteinemia.[2]

References

Metanx package insert, 2014
Smith HS, Pappagallo M (2012). "Metanx: Folate, B₆, B₁₂ Vitamins Combination". Essential Pain Pharmacology: The Prescriber's Guide. Cambridge University Press. p. 521. ISBN 978-0-521-75910-6.(Google Books)
Liptan G (2016). The FibroManual: A Complete Fibromyalgia Treatment Guide for You and Your Doctor. Ballantine Books. p. 237. ISBN 9781101967201.(Google Books)

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[1] Metanx package insert, 2014

[espain-2] Smith HS, Pappagallo M (2012). "Metanx: Folate, B₆, B₁₂ Vitamins Combination". Essential Pain Pharmacology: The Prescriber's Guide. Cambridge University Press. p. 521. ISBN 978-0-521-75910-6.(Google Books)

[3] Liptan G (2016). The FibroManual: A Complete Fibromyalgia Treatment Guide for You and Your Doctor. Ballantine Books. p. 237. ISBN 9781101967201.(Google Books)