Metazosin

Metazosin is an antihypertensive alpha-adrenergic antagonist.[1][2]

Metazosin
Names
IUPAC name
1-[4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-2-methoxypropan-1-one
Other names
Kenosin
Identifiers
3D model (JSmol)
ChemSpider
Properties
C18H25N5O4
Molar mass 375.429 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. Trcka, V; König, J; Mácová, S; Smíd, M; Helfert, I; Votavová, M; Remesová, J; Nezádalová, E (1990). "Pharmacology of a new antihypertensive agent, metazosin (Kenosin)". Ceskoslovenska farmacie. 39 (6): 266–74. PMID 1981860.
  2. Lapka, R; Rejholec, V; Sechser, T; Peterková, M; Smíd, M (1989). "Interspecies pharmacokinetic scaling of metazosin, a novel alpha-adrenergic antagonist". Biopharmaceutics & drug disposition. 10 (6): 581–9. PMID 2575403.


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