NDC1

Nucleoporin NDC1 is a protein that in humans is encoded by the TMEM48 gene.[5][6][7] It anchors aladin to the nuclear pore complex.[8]

NDC1
Identifiers
AliasesNDC1, NET3, TMEM48, NDC1 transmembrane nucleoporin
External IDsOMIM: 610115 MGI: 1920037 HomoloGene: 41224 GeneCards: NDC1
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p32.3Start53,765,478 bp[1]
End53,838,463 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

55706

72787

Ensembl

ENSG00000058804

ENSMUSG00000028614

UniProt

Q9BTX1

Q8VCB1

RefSeq (mRNA)

NM_001168551
NM_018087

NM_028355

RefSeq (protein)

NP_001162023
NP_060557

NP_082631

Location (UCSC)Chr 1: 53.77 – 53.84 MbChr 4: 107.37 – 107.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000058804 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000028614 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Lau CK, Delmar VA, Forbes DJ (Aug 2006). "Topology of yeast Ndc1p: predictions for the human NDC1/NET3 homologue". Anat Rec a Discov Mol Cell Evol Biol. 288 (7): 681–94. doi:10.1002/ar.a.20335. PMC 3049984. PMID 16779818.
  6. Schirmer EC, Florens L, Guan T, Yates JR 3rd, Gerace L (Sep 2003). "Nuclear membrane proteins with potential disease links found by subtractive proteomics". Science. 301 (5638): 1380–2. Bibcode:2003Sci...301.1380S. doi:10.1126/science.1088176. PMID 12958361. S2CID 23832536.
  7. "Entrez Gene: TMEM48 transmembrane protein 48".
  8. Kind, Barbara; Koehler, Katrin; Lorenz, Mike; Huebner, Angela (December 2009). "The nuclear pore complex protein ALADIN is anchored via NDC1 but not via POM121 and GP210 in the nuclear envelope". Biochemical and Biophysical Research Communications. 390 (2): 205–210. doi:10.1016/j.bbrc.2009.09.080. PMID 19782045.

Further reading


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