NECAP2

Adaptin ear-binding coat-associated protein 2 is a protein that in humans is encoded by the NECAP2 gene.[5][6][7]

NECAP2
Identifiers
AliasesNECAP2, NECAP endocytosis associated 2
External IDsOMIM: 611624 MGI: 1913397 HomoloGene: 9168 GeneCards: NECAP2
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p36.13Start16,440,721 bp[1]
End16,460,078 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

55707

66147

Ensembl

ENSG00000157191

ENSMUSG00000028923

UniProt

Q9NVZ3

Q9D1J1

RefSeq (mRNA)

NM_001145277
NM_001145278
NM_018090

NM_025383

RefSeq (protein)

NP_001138749
NP_001138750
NP_060560

NP_079659

Location (UCSC)Chr 1: 16.44 – 16.46 MbChr 4: 141.07 – 141.08 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

NECAP2 has been shown to interact with AP1G1.[8]

References

  1. GRCh38: Ensembl release 89: ENSG00000157191 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000028923 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ritter B, Philie J, Girard M, Tung EC, Blondeau F, McPherson PS (Oct 2003). "Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif". EMBO Rep. 4 (11): 1089–95. doi:10.1038/sj.embor.embor7400004. PMC 1326374. PMID 14555962.
  6. Ritter B, Blondeau F, Denisov AY, Gehring K, McPherson PS (Oct 2004). "Molecular mechanisms in clathrin-mediated membrane budding revealed through subcellular proteomics". Biochem. Soc. Trans. 32 (Pt 5): 769–73. doi:10.1042/BST0320769. PMID 15494011.
  7. "Entrez Gene: NECAP2 NECAP endocytosis associated 2".
  8. Mattera R, Ritter B, Sidhu SS, McPherson PS, Bonifacino JS (Feb 2004). "Definition of the consensus motif recognized by gamma-adaptin ear domains". J. Biol. Chem. 279 (9): 8018–28. doi:10.1074/jbc.M311873200. PMID 14665628.

Further reading


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