NOSIP

NOSIP
Identifiers
Aliases	NOSIP, CGI-25, nitric oxide synthase interacting protein
External IDs	OMIM: 616759 MGI: 1913644 HomoloGene: 9315 GeneCards: NOSIP
Gene location (Human)
Chr.	Chromosome 19 (human)[1]
End	49,590,262 bp[1]
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)[2]
End	45,078,210 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• GO:0001948 protein binding; • transferase activity; • RNA binding; • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity;
Cellular component	• cytoplasm; • cytosol; • Golgi membrane; • cell nucleus;
Biological process	• GO:0048553 negative regulation of catalytic activity; • negative regulation of nitric-oxide synthase activity; • multicellular organism development; • protein ubiquitination; • regulation of nitric-oxide synthase activity;
	Sources:Amigo / QuickGO
Orthologs
	51070
	66394
	ENSG00000142546
	ENSMUSG00000003421
	Q9Y314
	Q9D6T0
	NM_001270960; NM_015953; NM_001363649
	NM_001163684; NM_025533
	NP_001257889; NP_057037; NP_001350578
	NP_001157156; NP_079809
	Wikidata
View/Edit Human	View/Edit Mouse

Nitric oxide synthase-interacting protein is an enzyme that in humans is encoded by the NOSIP gene.[5][6][7]

References

GRCh38: Ensembl release 89: ENSG00000142546 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000003421 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Dedio J, Konig P, Wohlfart P, Schroeder C, Kummer W, Muller-Esterl W (Jan 2001). "NOSIP, a novel modulator of endothelial nitric oxide synthase activity". FASEB J. 15 (1): 79–89. doi:10.1096/fj.00-0078com. PMID 11149895. S2CID 34485514.
Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
"Entrez Gene: NOSIP nitric oxide synthase interacting protein".

Schleicher M, Brundin F, Gross S, et al. (2005). "Cell cycle-regulated inactivation of endothelial NO synthase through NOSIP-dependent targeting to the cytoskeleton". Mol. Cell. Biol. 25 (18): 8251–8. doi:10.1128/MCB.25.18.8251-8258.2005. PMC 1234313. PMID 16135813.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Dreyer J, Schleicher M, Tappe A, et al. (2005). "Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity". J. Neurosci. 24 (46): 10454–65. doi:10.1523/JNEUROSCI.2265-04.2004. PMC 6730309. PMID 15548660.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

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