NUDC

Nuclear migration protein nudC is a protein that in humans is encoded by the NUDC gene.[5]

NUDC
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNUDC, HMNPD011, nudC nuclear distribution protein, nuclear distribution C, dynein complex regulator
External IDsOMIM: 610325 MGI: 106014 HomoloGene: 4812 GeneCards: NUDC
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p36.11Start26,900,238 bp[1]
End26,946,871 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

10726

18221

Ensembl

ENSG00000090273

ENSMUSG00000028851

UniProt

Q9Y266

O35685

RefSeq (mRNA)

NM_006600

NM_010948

RefSeq (protein)

NP_006591

NP_035078

Location (UCSC)Chr 1: 26.9 – 26.95 MbChr 4: 133.53 – 133.55 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

NUDC has been shown to interact with PLK1[6] and PAFAH1B1.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000090273 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000028851 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: NUDC nuclear distribution gene C homolog (A. nidulans)".
  6. Zhou T, Aumais JP, Liu X, Yu-Lee LY, Erikson RL (Jul 2003). "A role for Plk1 phosphorylation of NudC in cytokinesis". Developmental Cell. 5 (1): 127–38. doi:10.1016/S1534-5807(03)00186-2. PMID 12852857.
  7. Morris SM, Albrecht U, Reiner O, Eichele G, Yu-Lee LY (May 1998). "The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC". Current Biology. 8 (10): 603–6. doi:10.1016/S0960-9822(98)70232-5. PMID 9601647.

Further reading

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