Narciclasine
Narciclasine is a toxic alkaloid found in various Amaryllidaceae species.[1]
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IUPAC name
(2S-(2α,3β,4β,4aβ))-3,4,4a,5-Tetrahydro-2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthridin-6(2H)-one | |
Other names
BRN 1087400, Lycoricidin-A, Lycoricidinol, NSC 266535 | |
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3D model (JSmol) |
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ChemSpider | |
ECHA InfoCard | 100.214.093 |
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Properties | |
C14H13NO7 | |
Molar mass | 307.258 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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References
- Kornienko A, Evidente A (2008). "Chemistry, biology, and medicinal potential of narciclasine and its congeners". Chem Rev. 108 (6): 1982–2014. doi:10.1021/cr078198u. PMC 2856661. PMID 18489166.
Bibliography
- Gwendoline Van Goietsenoven; Véronique Mathieu; Florence Lefranc; Alexander Kornienko; Antonio Evidente; Robert Kiss (March 2013). "Narciclasine as well as other Amaryllidaceae Isocarbostyrils are Promising GTP-ase Targeting Agents against Brain Cancers". Medicinal Research Reviews. 33 (2): 439–455. doi:10.1002/med.21253.
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