Nolatrexed
Nolatrexed is a thymidylate synthase inhibitor.[1][2]
 | |
| Names | |
|---|---|
| IUPAC name
2-Amino-6-methyl-5-(4-pyridylthio)-1H-quinazolin-4-one | |
| Identifiers | |
3D model (JSmol) |
|
| ChemSpider | |
PubChem CID |
|
| UNII | |
CompTox Dashboard (EPA) |
|
| |
| |
| Properties | |
| C14H12N4OS | |
| Molar mass | 284.34 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is  ?) | |
| Infobox references | |
References
- Hughes AN, Rafi I, Griffin MJ, et al. (January 1999). "Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days". Clin. Cancer Res. 5 (1): 111–8. PMID 9918208.
- "Nolatrexed". PubChem.gov. Pub Chem. Retrieved 12 August 2014.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.