Oxaloacetase

In enzymology, an oxaloacetase (EC 3.7.1.1) is an enzyme that catalyzes the chemical reaction:[1]

oxaloacetate + H2O oxalate + acetate
oxaloacetase
Identifiers
EC number3.7.1.1
CAS number9024-89-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are oxaloacetate and H2O, whereas its two products are oxalate and acetate.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is oxaloacetate acetylhydrolase. This enzyme is also called oxalacetic hydrolase.

References
  1. Gadd GM (1999). "Fungal production of citric and oxalic acid: importance in metal speciation, physiology and biogeochemical processes". Adv. Microb. Physiol. 41: 47–92. doi:10.1016/s0065-2911(08)60165-4. PMID 10500844.

See also
  • Hayaishi O, Shimazono H, Katagiri M, Saito Y (1956). "Enzymatic formation of oxalate and acetate from oxaloacetate". J. Am. Chem. Soc. 78 (19): 5126–5127. doi:10.1021/ja01600a084.


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