PABPC5
Poly(A) binding protein cytoplasmic 5 is a protein that in humans is encoded by the PABPC5 gene. [4]
| PABPC5 | |||||||||||||||||||||||||
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| Aliases | PABPC5, PABP5, poly(A) binding protein cytoplasmic 5 | ||||||||||||||||||||||||
| External IDs | OMIM: 300407 MGI: 2136401 HomoloGene: 5857 GeneCards: PABPC5 | ||||||||||||||||||||||||
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| Species | Human | Mouse | |||||||||||||||||||||||
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| Location (UCSC) | Chr X: 91.43 – 91.44 Mb | n/a | |||||||||||||||||||||||
| PubMed search | [2] | [3] | |||||||||||||||||||||||
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Function
This gene encodes a poly(A)-binding protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010].
References
- GRCh38: Ensembl release 89: ENSG00000174740 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: Poly(A) binding protein cytoplasmic 5". Retrieved 2020-04-16.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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