PAPLN

PAPLN
Identifiers
Aliases	PAPLN, papilin, proteoglycan like sulfated glycoprotein, PPN
External IDs	OMIM: 617785 MGI: 2386139 HomoloGene: 71541 GeneCards: PAPLN
Gene location (Human)
Chr.	Chromosome 14 (human)[1]
End	73,274,640 bp[1]
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)[2]
End	83,792,382 bp[2]
Gene ontology
Molecular function	• peptidase inhibitor activity; • peptidase activity; • serine-type endopeptidase inhibitor activity;
Cellular component	• extracellular region;
Biological process	• negative regulation of peptidase activity; • negative regulation of endopeptidase activity; • proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	89932
	170721
	ENSG00000100767
	ENSMUSG00000021223
	O95428
	Q9EPX2
	NM_173462; NM_001365906; NM_001365907
	NM_001205343; NM_130887
	NP_775733; NP_001352835; NP_001352836
	NP_001192272; NP_570957
	Wikidata
View/Edit Human	View/Edit Mouse

Papilin is a protein that in humans is encoded by the PAPLN gene.[5][6][7] Papilin is an extracellular matrix glycoprotein.

References

GRCh38: Ensembl release 89: ENSG00000100767 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000021223 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: papilin".
Kramerova IA, Kawaguchi N, Fessler LI, Nelson RE, Chen Y, Kramerov AA, Kusche-Gullberg M, Kramer JM, Ackley BD, Sieron AL, Prockop DJ, Fessler JH (December 2000). "Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases". Development. 127 (24): 5475–85. PMID 11076767.
Apte SS (November 2009). "A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms". J. Biol. Chem. 284 (46): 31493–7. doi:10.1074/jbc.R109.052340. PMC 2797218. PMID 19734141.

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