PCDH7

Protocadherin-7 is a protein that in humans is encoded by the PCDH7 gene.[5][6]

PCDH7
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesPCDH7, BH-Pcdh, BHPCDH, PPP1R120, protocadherin 7
External IDsOMIM: 602988 MGI: 1860487 HomoloGene: 36101 GeneCards: PCDH7
Gene location (Human)
Chr.Chromosome 4 (human)[1]
Band4p15.1Start30,720,415 bp[1]
End31,146,805 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

5099

54216

Ensembl

ENSG00000169851

ENSMUSG00000029108

UniProt

O60245

n/a

RefSeq (mRNA)

NM_001173523
NM_002589
NM_032456
NM_032457

NM_001122758
NM_018764
NM_001310606
NM_001310608

RefSeq (protein)

NP_001166994
NP_002580
NP_115832
NP_115833

n/a

Location (UCSC)Chr 4: 30.72 – 31.15 MbChr 5: 57.72 – 58.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell–cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000169851 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000029108 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Yoshida K, Yoshitomo-Nakagawa K, Seki N, Sasaki M, Sugano S (Aug 1998). "Cloning, expression analysis, and chromosomal localization of BH-protocadherin (PCDH7), a novel member of the cadherin superfamily". Genomics. 49 (3): 458–61. doi:10.1006/geno.1998.5271. PMID 9615233.
  6. "Entrez Gene: PCDH7 protocadherin 7".

Further reading


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