PLEK2

Pleckstrin-2 is a protein that in humans is encoded by the PLEK2 gene.[5][6][7] The PLEK2 gene is located on chromosome 14 in Homo sapiens and is flanked by TMEM229B to its right and ATP6V1D to its left.[8]

PLEK2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPLEK2, pleckstrin 2
External IDsOMIM: 608007 MGI: 1351466 HomoloGene: 8447 GeneCards: PLEK2
Gene location (Human)
Chr.Chromosome 14 (human)[1]
Band14q23.3-q24.1Start67,386,984 bp[1]
End67,412,167 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

26499

27260

Ensembl

ENSG00000100558

ENSMUSG00000021118

UniProt

Q9NYT0

Q9WV52

RefSeq (mRNA)

NM_016445

NM_013738

RefSeq (protein)

NP_057529

NP_038766

Location (UCSC)Chr 14: 67.39 – 67.41 MbChr 12: 78.89 – 78.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References

  1. GRCh38: Ensembl release 89: ENSG00000100558 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000021118 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Lemmon, Mark A.; Ferguson, Kathryn M.; Abrams, Charles S. (2002). "Pleckstrin homology domains and the cytoskeleton". FEBS Letters. 513 (1): 71–76. doi:10.1016/S0014-5793(01)03243-4. PMID 11911883.
  6. Hamaguchi N, Ihara S, Ohdaira T, Nagano H, Iwamatsu A, Tachikawa H, Fukui Y (Aug 2007). "Pleckstrin-2 selectively interacts with phosphatidylinositol 3-kinase lipid products and regulates actin organization and cell spreading". Biochem Biophys Res Commun. 361 (2): 270–5. doi:10.1016/j.bbrc.2007.06.132. PMID 17658464.
  7. "Entrez Gene: PLEK2 pleckstrin 2".
  8. "AceView: PLEK2 gene". AceView. National Library of Medicine. Retrieved 24 April 2011.

Further reading


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