PNPLA8

Calcium-independent phospholipase A2-gamma is an enzyme that in humans is encoded by the PNPLA8 gene.[5][6][7][8][9]

PNPLA8
Identifiers
AliasesPNPLA8, IPLA2(GAMMA), IPLA2-2, IPLA2G, iPLA2gamma, MMLA, PNPLA-gamma, patatin like phospholipase domain containing 8
External IDsOMIM: 612123 MGI: 1914702 HomoloGene: 12136 GeneCards: PNPLA8
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q31.1Start108,470,417 bp[1]
End108,569,666 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

50640

67452

Ensembl

ENSG00000135241

ENSMUSG00000036257

UniProt

Q9NP80

Q8K1N1

RefSeq (mRNA)

NM_026164

RefSeq (protein)

NP_080440

Location (UCSC)Chr 7: 108.47 – 108.57 MbChr 12: 44.22 – 44.32 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References

  1. GRCh38: Ensembl release 89: ENSG00000135241 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000036257 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Mancuso DJ, Jenkins CM, Gross RW (May 2000). "The genomic organization, complete mRNA sequence, cloning, and expression of a novel human intracellular membrane-associated calcium-independent phospholipase A(2)". J Biol Chem. 275 (14): 9937–45. doi:10.1074/jbc.275.14.9937. PMID 10744668.
  6. Tanaka H, Takeya R, Sumimoto H (Jul 2000). "A novel intracellular membrane-bound calcium-independent phospholipase A(2)". Biochem Biophys Res Commun. 272 (2): 320–6. doi:10.1006/bbrc.2000.2776. PMID 10833412.
  7. Wilson PA, Gardner SD, Lambie NM, Commans SA, Crowther DJ (Aug 2006). "Characterization of the human patatin-like phospholipase family". J Lipid Res. 47 (9): 1940–9. doi:10.1194/jlr.M600185-JLR200. PMID 16799181.
  8. Kienesberger PC, Oberer M, Lass A, Zechner R (Apr 2009). "Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions". J Lipid Res. 50 Suppl (Supplement): S63–8. doi:10.1194/jlr.R800082-JLR200. PMC 2674697. PMID 19029121.
  9. "Entrez Gene: PNPLA8 patatin-like phospholipase domain containing 8".

Further reading


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