PPIG (gene)

Peptidyl-prolyl cis-trans isomerase G is an enzyme that in humans is encoded by the PPIG gene.[5][6][7]

PPIG
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPPIG, CARS-Cyp, CYP, SCAF10, SRCyp, peptidylprolyl isomerase G
External IDsOMIM: 606093 MGI: 2445173 HomoloGene: 3520 GeneCards: PPIG
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2q31.1Start169,584,344 bp[1]
End169,641,406 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9360

228005

Ensembl

ENSG00000138398

ENSMUSG00000042133

UniProt

Q13427

A2AR02

RefSeq (mRNA)

NM_004792

NM_001081086

RefSeq (protein)

NP_004783

NP_001074555

Location (UCSC)Chr 2: 169.58 – 169.64 MbChr 2: 69.72 – 69.75 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

PPIG (gene) has been shown to interact with Pinin.[8]

References

  1. GRCh38: Ensembl release 89: ENSG00000138398 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000042133 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Nestel FP, Colwill K, Harper S, Pawson T, Anderson SK (Jan 1997). "RS cyclophilins: identification of an NK-TR1-related cyclophilin". Gene. 180 (1–2): 151–5. doi:10.1016/S0378-1119(96)00436-2. PMID 8973360.
  6. Bourquin JP, Stagljar I, Meier P, Moosmann P, Silke J, Baechi T, Georgiev O, Schaffner W (Jul 1997). "A serine/arginine-rich nuclear matrix cyclophilin interacts with the C-terminal domain of RNA polymerase II". Nucleic Acids Res. 25 (11): 2055–61. doi:10.1093/nar/25.11.2055. PMC 146702. PMID 9153302.
  7. "Entrez Gene: PPIG peptidylprolyl isomerase G (cyclophilin G)".
  8. Lin, Chun Lun; Leu Steve; Lu Ming Chu; Ouyang Pin (Aug 2004). "Over-expression of SR-cyclophilin, an interaction partner of nuclear pinin, releases SR family splicing factors from nuclear speckles". Biochem. Biophys. Res. Commun. United States. 321 (3): 638–47. doi:10.1016/j.bbrc.2004.07.013. ISSN 0006-291X. PMID 15358154.

Further reading

  • Overview of all the structural information available in the PDB for UniProt: Q13427 (Peptidyl-prolyl cis-trans isomerase G) at the PDBe-KB.


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