PPP1R11

Protein phosphatase 1 regulatory subunit 11 is an enzyme that in humans is encoded by the PPP1R11 gene.[5][6][7]

PPP1R11
Identifiers
AliasesPPP1R11, HCG-V, HCGV, IPP3, TCTE5, TCTEX5, CFAP255, protein phosphatase 1 regulatory inhibitor subunit 11
External IDsOMIM: 606670 MGI: 1923747 HomoloGene: 32520 GeneCards: PPP1R11
Gene location (Human)
Chr.Chromosome 6 (human)[1]
Band6p22.1Start30,066,709 bp[1]
End30,070,333 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

6992

76497

Ensembl

ENSMUSG00000036398

UniProt

O60927

Q8K1L5

RefSeq (mRNA)

NM_021959
NM_170781

NM_029632

RefSeq (protein)

NP_068778
NP_068778.1

NP_083908

Location (UCSC)Chr 6: 30.07 – 30.07 MbChr 17: 36.95 – 36.95 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a specific inhibitor of protein phosphatase-1 (PP1) with a differential sensitivity toward the metal-independent and metal-dependent forms of PP1.

The gene is located within the major histocompatibility complex class I region on chromosome 6.[7]

References

  1. ENSG00000236560, ENSG00000237829, ENSG00000204619, ENSG00000237403, ENSG00000233314, ENSG00000206501, ENSG00000227720 GRCh38: Ensembl release 89: ENSG00000234058, ENSG00000236560, ENSG00000237829, ENSG00000204619, ENSG00000237403, ENSG00000233314, ENSG00000206501, ENSG00000227720 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000036398 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Zhang J, Zhang L, Zhao S, Lee EY (Dec 1998). "Identification and characterization of the human HCG V gene product as a novel inhibitor of protein phosphatase-1". Biochemistry. 37 (47): 16728–34. doi:10.1021/bi981169g. PMID 9843442.
  6. Giffon T, Lepourcelet M, Pichon L, Jezequel P, Bouric P, Carn G, Pontarotti P, Gall JY, David V (Oct 1996). "Cloning of a human homologue of the mouse Tctex-5 gene within the MHC class I region". Immunogenetics. 44 (5): 331–9. doi:10.1007/BF02602777. PMID 8781118. S2CID 7130465.
  7. "Entrez Gene: PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11".

Further reading


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