PPP2R3C

PPP2R3C
Identifiers
Aliases	PPP2R3C, C14orf10, G4-1, G5pr, protein phosphatase 2 regulatory subunit Bgamma, SPGF36, GDRM
External IDs	OMIM: 615902 MGI: 1930009 HomoloGene: 9915 GeneCards: PPP2R3C
Gene location (Human)
Chr.	Chromosome 14 (human)[1]
End	35,122,517 bp[1]
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)[2]
End	55,302,998 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• GO:0001948 protein binding; • metal ion binding;
Cellular component	• cytoplasm; • centrosome; • spindle; • cell nucleus; • Golgi apparatus; • cytosol;
Biological process	• positive regulation of B cell differentiation; • regulation of B cell activation; • cortical cytoskeleton organization; • B cell homeostasis; • spleen development; • activation of protein kinase activity; • microtubule cytoskeleton organization; • regulation of mitochondrial depolarization; • regulation of antimicrobial humoral response; • T cell homeostasis; • regulation of dephosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	55012
	59032
	ENSG00000092020
	ENSMUSG00000021022
	Q969Q6
	Q9JK24
	NM_001305155; NM_001305156; NM_017917
	NM_021529
	NP_001292084; NP_001292085; NP_060387
	NP_067504
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma is an enzyme that in humans is encoded by the PPP2R3C gene.[5][6][7]

References

GRCh38: Ensembl release 89: ENSG00000092020 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000021022 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Kono Y, Maeda K, Kuwahara K, Yamamoto H, Miyamoto E, Yonezawa K, Takagi K, Sakaguchi N (Aug 2002). "MCM3-binding GANP DNA-primase is associated with a novel phosphatase component G5PR". Genes Cells. 7 (8): 821–34. doi:10.1046/j.1365-2443.2002.00562.x. PMID 12167160.
Xing Y, Igarashi H, Wang X, Sakaguchi N (Sep 2005). "Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor–induced apoptosis". J Exp Med. 202 (5): 707–19. doi:10.1084/jem.20050637. PMC 2212881. PMID 16129705.
"Entrez Gene: PPP2R3C protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma".

Kamnasaran D, Chen CP, Devriendt K, et al. (2005). "Defining a holoprosencephaly locus on human chromosome 14q13 and characterization of potential candidate genes". Genomics. 85 (5): 608–21. doi:10.1016/j.ygeno.2005.01.010. PMID 15820313.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000092020 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021022 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12167160-5] Kono Y, Maeda K, Kuwahara K, Yamamoto H, Miyamoto E, Yonezawa K, Takagi K, Sakaguchi N (Aug 2002). "MCM3-binding GANP DNA-primase is associated with a novel phosphatase component G5PR". Genes Cells. 7 (8): 821–34. doi:10.1046/j.1365-2443.2002.00562.x. PMID 12167160.

[pmid16129705-6] Xing Y, Igarashi H, Wang X, Sakaguchi N (Sep 2005). "Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor–induced apoptosis". J Exp Med. 202 (5): 707–19. doi:10.1084/jem.20050637. PMC 2212881. PMID 16129705.

[entrez-7] "Entrez Gene: PPP2R3C protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma".

PPP2R3C

References

Further reading