Pentafluorophenol

Pentafluorophenol is the organofluorine compound (specifically a fluoroalcohol) with the formula C6F5OH. It is a colorless solid that melts just above room temperature. With a pKa of 5.5, it is one of the most acidic phenols. It is used to prepare pentafluorophenyl esters, which are active esters useful in peptide synthesis.[1]

Pentafluorophenol
Names
IUPAC name
2,3,4,5,6-pentafluorophenol
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.011.123
EC Number
  • 212-235-8
UNII
Properties
C6HF5O
Molar mass 184.065 g·mol−1
Appearance white solid or colorless liquid
Melting point 32.8 °C (91.0 °F; 305.9 K)
Boiling point 145.6 °C (294.1 °F; 418.8 K)
Hazards
GHS pictograms
GHS Signal word Danger
H302, H312, H314, H315, H319, H335
P260, P261, P264, P270, P271, P280, P301+312, P301+330+331, P302+352, P303+361+353, P304+340, P305+351+338, P310, P312, P321, P322, P330, P332+313, P337+313, P362, P363, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. Jones, Keith; DeAmicis, Carl (2009). "Pentafluorophenol". Encyclopedia of Reagents for Organic Synthesis. pp. 1–9. doi:10.1002/047084289X.rp026.CS1 maint: uses authors parameter (link)
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.