Piperlongumine
Piperlongumine (also called piplartine or piperlongumin) is an amide alkaloid constituent[1] of the fruit of the long pepper (Piper longum), a pepper plant found in southern India and southeast Asia.[2] When extracted, piperlongumine may cause skin, eye or respiratory tract irritation.[1]
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| Names | |
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| IUPAC name
1-[(2E)-3-(3,4,5-Trimethoxyphenyl)prop-2-enoyl]-5,6-dihydropyridin-2(1H)-one | |
| Other names
Piplartine | |
| Identifiers | |
3D model (JSmol) |
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| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.243.690  |
PubChem CID |
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| Properties | |
| C17H19NO5 | |
| Molar mass | 317.341 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is  ?) | |
| Infobox references | |
Traditional medicine and research
Long peppers have been used in Ayurveda and traditional Chinese medicine as a supposed treatment.[2][3] As a constituent of long peppers, piperlongumine has been assessed in laboratory studies to determine its possible biological properties.[2][3]
References
- "Piperlongumine". PubChem, US National Library of Medicine. 29 November 2020. Retrieved 5 December 2020.
- Piska, Kamil; Gunia-Krzyżak, Agnieszka; Koczurkiewicz, Paulina; Wójcik-Pszczoła, Katarzyna; Pękala, Elżbieta (2018). "Piperlongumine (piplartine) as a lead compound for anticancer agents – Synthesis and properties of analogues: A mini-review". European Journal of Medicinal Chemistry. 156: 13–20. doi:10.1016/j.ejmech.2018.06.057. ISSN 0223-5234. PMID 30006159.
- "Piperlongumine". US National Center for Advancing Translational Sciences. 2020. Retrieved 5 December 2020.
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