RB1CC1

RB1-inducible coiled-coil protein 1 is a protein that in humans is encoded by the RB1CC1 gene.[5][6][7][8]

RB1CC1
Identifiers
AliasesRB1CC1, ATG17, CC1, FIP200, PPP1R131, RB1 inducible coiled-coil 1
External IDsOMIM: 606837 MGI: 1341850 HomoloGene: 7659 GeneCards: RB1CC1
Gene location (Human)
Chr.Chromosome 8 (human)[1]
Band8q11.23Start52,622,458 bp[1]
End52,745,843 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9821

12421

Ensembl

ENSG00000023287

ENSMUSG00000025907

UniProt

Q8TDY2

Q9ESK9

RefSeq (mRNA)

NM_001083617
NM_014781

NM_009826

RefSeq (protein)

NP_001077086
NP_055596

NP_033956

Location (UCSC)Chr 8: 52.62 – 52.75 MbChr 1: 6.21 – 6.28 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

RB1CC1 has been shown to interact with PTK2B,[9] ASK1[10] and PTK2.[9]

References

  1. GRCh38: Ensembl release 89: ENSG00000023287 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000025907 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Chano T, Ikegawa S, Kontani K, Okabe H, Baldini N, Saeki Y (Feb 2002). "Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells". Oncogene. 21 (8): 1295–8. doi:10.1038/sj.onc.1205171. PMID 11850849. S2CID 1446211.
  6. Maucuer A, Camonis JH, Sobel A (Apr 1995). "Stathmin interaction with a putative kinase and coiled-coil-forming protein domains". Proceedings of the National Academy of Sciences of the United States of America. 92 (8): 3100–4. doi:10.1073/pnas.92.8.3100. PMC 42112. PMID 7724523.
  7. Hara T, Takamura A, Kishi C, Iemura S, Natsume T, Guan JL, Mizushima N (May 2008). "FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells". The Journal of Cell Biology. 181 (3): 497–510. doi:10.1083/jcb.200712064. PMC 2364687. PMID 18443221.
  8. "Entrez Gene: RB1CC1 RB1-inducible coiled-coil 1".
  9. Ueda H, Abbi S, Zheng C, Guan JL (Apr 2000). "Suppression of Pyk2 kinase and cellular activities by FIP200". The Journal of Cell Biology. 149 (2): 423–30. doi:10.1083/jcb.149.2.423. PMC 2175150. PMID 10769033.
  10. Gan B, Peng X, Nagy T, Alcaraz A, Gu H, Guan JL (Oct 2006). "Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways". The Journal of Cell Biology. 175 (1): 121–33. doi:10.1083/jcb.200604129. PMC 2064504. PMID 17015619.

Further reading

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