RBM15

Putative RNA-binding protein 15 is a protein that in humans is encoded by the RBM15 gene.[4][5][6] It is a RNA-binding protein that acts as a key regulator of N6-Methyladenosine (m6A) methylation of RNAs[7]

RBM15
Identifiers
AliasesRBM15, OTT, OTT1, SPEN, RNA binding motif protein 15, Putative RNA-binding protein 15
External IDsOMIM: 606077 MGI: 2443205 HomoloGene: 23383 GeneCards: RBM15
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p13.3Start110,338,506 bp[1]
End110,346,681 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

64783

229700

Ensembl

ENSG00000162775

ENSMUSG00000048109

UniProt

Q96T37

Q0VBL3

RefSeq (mRNA)

NM_001201545
NM_022768

NM_001045807

RefSeq (protein)

NP_001188474
NP_073605

NP_001039272

Location (UCSC)Chr 1: 110.34 – 110.35 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse


References

  1. GRCh38: Ensembl release 89: ENSG00000162775 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. Ma Z, Morris SW, Valentine V, Li M, Herbrick JA, Cui X, Bouman D, Li Y, Mehta PK, Nizetic D, Kaneko Y, Chan GC, Chan LC, Squire J, Scherer SW, Hitzler JK (Jun 2001). "Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia". Nat Genet. 28 (3): 220–1. doi:10.1038/90054. PMID 11431691. S2CID 36236342.
  5. Mercher T, Coniat MB, Monni R, Mauchauffe M, Nguyen Khac F, Gressin L, Mugneret F, Leblanc T, Dastugue N, Berger R, Bernard OA (May 2001). "Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia". Proc Natl Acad Sci U S A. 98 (10): 5776–9. Bibcode:2001PNAS...98.5776M. doi:10.1073/pnas.101001498. PMC 33289. PMID 11344311.
  6. "Entrez Gene: RBM15 RNA binding motif protein 15".
  7. "UniProtKB - Q96T37 (RBM15_HUMAN)". Retrieved 29 October 2018.

Further reading


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