RRP12

RRP12-like protein is a protein that in humans is encoded by the RRP12 gene.[5][6] It is currently thought to be involved in ribosome assembly of the precursor particles of both subunits in eukaryotes and was identified as a RNA binding protein.[7][8]

RRP12
Identifiers
AliasesRRP12, KIAA0690, ribosomal RNA processing 12 homolog
External IDsOMIM: 617723 MGI: 2147437 HomoloGene: 22370 GeneCards: RRP12
Gene location (Human)
Chr.Chromosome 10 (human)[1]
Band10q24.1Start97,356,358 bp[1]
End97,426,076 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

23223

107094

Ensembl

ENSG00000052749

ENSMUSG00000035049

UniProt

Q5JTH9

Q6P5B0

RefSeq (mRNA)

NM_001145114
NM_001284337
NM_015179

NM_199447

RefSeq (protein)

NP_001138586
NP_001271266
NP_055994

NP_955518

Location (UCSC)Chr 10: 97.36 – 97.43 MbChr 19: 41.86 – 41.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000052749 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000035049 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (June 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
  6. "Entrez Gene: RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)".
  7. Oeffinger M, Dlakic M, Tollervey D (January 2004). "A pre-ribosome-associated HEAT-repeat protein is required for export of both ribosomal subunits". Genes & Development. 18 (2): 196–209. doi:10.1101/gad.285604. PMC 324425. PMID 14729571.
  8. Moriggi G, Nieto B, Dosil M (December 2014). "Rrp12 and the Exportin Crm1 participate in late assembly events in the nucleolus during 40S ribosomal subunit biogenesis". PLOS Genetics. 10 (12): e1004836. doi:10.1371/journal.pgen.1004836. PMC 4256259. PMID 25474739.

Further reading


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