RTN2

Reticulon-2 is a protein that in humans is encoded by the RTN2 gene.[5][6][7]

RTN2
Identifiers
AliasesRTN2, NSP2, NSPL1, NSPLI, SPG12, reticulon 2
External IDsOMIM: 603183 MGI: 107612 HomoloGene: 32180 GeneCards: RTN2
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19q13.32Start45,485,294 bp[1]
End45,497,055 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

6253

20167

Ensembl

ENSG00000125744

ENSMUSG00000030401

UniProt

O75298
Q96CG9

O70622

RefSeq (mRNA)

NM_206902
NM_005619
NM_206900
NM_206901

NM_001025364
NM_013648

RefSeq (protein)

NP_005610
NP_996783
NP_996784

NP_001020535
NP_038676

Location (UCSC)Chr 19: 45.49 – 45.5 MbChr 7: 19.28 – 19.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Alternatively spliced transcript variants encoding different isoforms have been identified.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000125744 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000030401 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Stubbs L, Carver EA, Shannon ME, Kim J, Geisler J, Generoso EE, Stanford BG, Dunn WC, Mohrenweiser H, Zimmermann W, Watt SM, Ashworth LK (Dec 1996). "Detailed comparative map of human chromosome 19q and related regions of the mouse genome". Genomics. 35 (3): 499–508. doi:10.1006/geno.1996.0390. PMID 8812484.
  6. Geisler JG, Stubbs LJ, Wasserman WW, Mucenski ML (May 1998). "Molecular cloning of a novel mouse gene with predominant muscle and neural expression". Mamm Genome. 9 (4): 274–82. doi:10.1007/s003359900748. PMID 9530622. S2CID 7091637.
  7. "Entrez Gene: RTN2 reticulon 2".

Further reading


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.