Ruth Dayhoff

Dayhoff is the daughter of Margaret Oakley Dayhoff, another early bioinformatician, and Edward S Dayhoff a distinguished Physicist in the area of Electro-optics. From a young age, Dayhoff was encouraged by her mother to pursue scientific interests.[1] In Dayhoff's words:

My mother was a science professor in a medical school and convinced me that I had to understand not only what physicians knew, but also how they worked and made decisions. I had always thought that computers would be important to the future of medicine and biology. I was interested in all of these areas as I was growing up, and I had a choice whether to study computer science or go to medical school. So I decided to go to medical school to better understand not only the treatment of patients but the actions and knowledge of physicians.[1]

Dayhoff complete her undergraduate studies at the University of Maryland. During her undergraduate career, she majored in mathematics. Dayhoff graduated in 1973 after only 3 years, earning the highest honors. She went on to attend medical school at Georgetown University School of Medicine and graduated in 1977. Dayhoff had started working on Computer systems while in High School. During her time at Georgetown, she began to pursue informatics. While in Medical School she authored the MUMPS Primer with Martin Johnson. Dayhoff completed her second residency in 1980 at Johns Hopkins University School of Medicine, where she studied clinical pathology and gave special attention to Laboratory Information Systems.[1] Dayhoff was one of the organizers of the original Symposium on Computer Applications in Medical Care. She was Elected a Founding Fellow of the American College of Medical Informatics in 1983.

Dayhoff pioneered integrated hospital digital imaging systems. She built a prototype demonstration system in her basement in Adelphi Md in 1985. Dayhoff has held high-ranking positions in the US Department of Veterans Affairs' VistA Imaging Project since 1989. She served as the national projects manager and retired as Director of Digital Imaging in Medicine. As national projects manager, she supervised integration of old patient records with the VA computerized system for patient records. This growing database of patient records is one of a kind on a global scale and has received much acclaim and recognition. This system is currently implemented at the VA Medical Center in Washington, D.C., where it has been running for twenty years, and at over 150 other medical institutions.[1] A version of the system was installed at the National Cancer institute of Egypt. Dayhoff was chosen by the National Library of Medicine as one of the outstanding women physicians in America who "changed the face of medicine".

Dayhoff is married with two daughters and three grandchildren. She has said that her husband, Vincent Brannigan, has provided invaluable support throughout the years by sharing household responsibilities.