SGSM1

SGSM1
Identifiers
Aliases	SGSM1, RUTBC2, small G protein signaling modulator 1
External IDs	OMIM: 611417 MGI: 107320 HomoloGene: 64485 GeneCards: SGSM1
Gene location (Human)
Chr.	Chromosome 22 (human)[1]
End	24,927,578 bp[1]
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)[2]
End	113,310,786 bp[2]
Gene ontology
Molecular function	• GO:0001948 protein binding; • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity; • Rab GTPase binding;
Cellular component	• Golgi apparatus; • membrane; • cytoplasm; • cytoplasmic vesicle membrane; • cytosol; • endomembrane system; • cytoplasmic vesicle;
Biological process	• GO:0032861, GO:0032862, GO:0032856 activation of GTPase activity; • intracellular protein transport; • regulation of vesicle fusion;
	Sources:Amigo / QuickGO
Orthologs
	129049
	52850
	ENSG00000167037
	ENSMUSG00000042216
	Q2NKQ1
	Q8BPQ7
	NM_133454; NM_001039948; NM_001098497; NM_001098498
	NM_001162965; NM_001254731; NM_172718; NM_001309526; NM_001309528
	NP_001035037; NP_001091967; NP_001091968; NP_597711
	NP_001156437; NP_001241660; NP_001296455; NP_001296457; NP_766306
	Wikidata
View/Edit Human	View/Edit Mouse

Small G protein signaling modulator 1 (SGSM1) also known as RUN and TBC1 domain-containing protein 2 (RUTBC2) and nurr1-interacting protein (NuIP)[5] is a protein in humans that is encoded by the SGSM1 gene.[6][7]

References

GRCh38: Ensembl release 89: ENSG00000167037 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000042216 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Luo Y, Xing F, Guiliano R, Federoff HJ (September 2008). "Identification of a novel nurr1-interacting protein". The Journal of Neuroscience. 28 (37): 9277–86. doi:10.1523/JNEUROSCI.3021-08.2008. PMID 18784308.
"Entrez Gene: Small G protein signaling modulator 1".
Yang H, Sasaki T, Minoshima S, Shimizu N (August 2007). "Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway". Genomics. 90 (2): 249–60. doi:10.1016/j.ygeno.2007.03.013. PMID 17509819.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000167037 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000042216 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid18784308-5] Luo Y, Xing F, Guiliano R, Federoff HJ (September 2008). "Identification of a novel nurr1-interacting protein". The Journal of Neuroscience. 28 (37): 9277–86. doi:10.1523/JNEUROSCI.3021-08.2008. PMID 18784308.

[entrez-6] "Entrez Gene: Small G protein signaling modulator 1".

[Yang_2007-7] Yang H, Sasaki T, Minoshima S, Shimizu N (August 2007). "Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway". Genomics. 90 (2): 249–60. doi:10.1016/j.ygeno.2007.03.013. PMID 17509819.