SH3GLB2

Endophilin-B2 is a protein that in humans is encoded by the SH3GLB2 gene.[5][6]

SH3GLB2
Identifiers
AliasesSH3GLB2, PP6569, PP9455, RRIG1, SH3 domain containing GRB2 like endophilin B2, SH3 domain containing GRB2 like, endophilin B2
External IDsOMIM: 609288 MGI: 2385131 HomoloGene: 10595 GeneCards: SH3GLB2
Gene location (Human)
Chr.Chromosome 9 (human)[1]
Band9q34.11Start129,007,036 bp[1]
End129,028,303 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

56904

227700

Ensembl

ENSG00000148341

ENSMUSG00000026860

UniProt

Q9NR46

Q8R3V5

RefSeq (mRNA)

NM_001289709
NM_001289710
NM_139302
NM_001346806
NM_001362888

RefSeq (protein)

NP_001276638
NP_001276639
NP_001333735
NP_647463
NP_001349817

Location (UCSC)Chr 9: 129.01 – 129.03 MbChr 2: 30.34 – 30.36 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

SH3GLB2 has been shown to interact with SH3GLB1[5] and SH3KBP1.[7][8]

References

  1. GRCh38: Ensembl release 89: ENSG00000148341 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000026860 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Pierrat B, Simonen M, Cueto M, Mestan J, Ferrigno P, Heim J (February 2001). "SH3GLB, a new endophilin-related protein family featuring an SH3 domain". Genomics. 71 (2): 222–34. doi:10.1006/geno.2000.6378. PMID 11161816.
  6. "Entrez Gene: SH3GLB2 SH3-domain GRB2-like endophilin B2".
  7. Petrelli A, Gilestro GF, Lanzardo S, Comoglio PM, Migone N, Giordano S (March 2002). "The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met". Nature. 416 (6877): 187–90. doi:10.1038/416187a. PMID 11894096. S2CID 4389099.
  8. Soubeyran P, Kowanetz K, Szymkiewicz I, Langdon WY, Dikic I (March 2002). "Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors". Nature. 416 (6877): 183–7. doi:10.1038/416183a. PMID 11894095. S2CID 635702.

Further reading


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