SOX30
Function
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
References
- "Entrez Gene: SRY (sex determining region Y)-box 30". Retrieved 2014-05-29.
Further reading
- Koopman, P; Schepers, G; Brenner, S; Venkatesh, B (2004). "Origin and diversity of the SOX transcription factor gene family: Genome-wide analysis in Fugu rubripes". Gene. 328: 177–86. doi:10.1016/j.gene.2003.12.008. PMID 15019997.
- Osaki, E; Nishina, Y; Inazawa, J; Copeland, N. G.; Gilbert, D. J.; Jenkins, N. A.; Ohsugi, M; Tezuka, T; Yoshida, M; Semba, K (1999). "Identification of a novel Sry-related gene and its germ cell-specific expression". Nucleic Acids Research. 27 (12): 2503–10. doi:10.1093/nar/27.12.2503. PMC 148454. PMID 10359848.
- Fan, B. J.; Wang, D. Y.; Tham, C. C.; Lam, D. S.; Pang, C. P. (2008). "Gene expression profiles of human trabecular meshwork cells induced by triamcinolone and dexamethasone". Investigative Ophthalmology & Visual Science. 49 (5): 1886–97. doi:10.1167/iovs.07-0414. PMID 18436822.
- Bullejos, M; Díaz de la Guardia R; Barragán, M. J.; Sánchez, A (2000). "HMG-box sequences from microbats homologous to the human SOX30 HMG-box". Genetica. 110 (2): 157–62. doi:10.1023/A:1017914005677. PMID 11678506.
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