STMN2

Stathmin-2 is a protein that in humans is encoded by the STMN2 gene.[5][6][7]

STMN2
Identifiers
AliasesSTMN2, SCG10, SCGN10, stathmin 2
External IDsOMIM: 600621 MGI: 98241 HomoloGene: 5102 GeneCards: STMN2
Gene location (Human)
Chr.Chromosome 8 (human)[1]
Band8q21.13Start79,610,814 bp[1]
End79,666,175 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

11075

20257

Ensembl

ENSG00000104435

ENSMUSG00000027500

UniProt

Q93045

P55821

RefSeq (mRNA)

NM_001199214
NM_007029

NM_025285

RefSeq (protein)

NP_001186143
NP_008960

NP_079561

Location (UCSC)Chr 8: 79.61 – 79.67 MbChr 3: 8.51 – 8.56 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

Superior cervical ganglion-10 is a neuronal growth-associated protein which shares significant amino acid sequence similarity with the phosphoprotein stathmin (MIM 151442).[supplied by OMIM][7]

Interactions

STMN2 has been shown to interact with RGS6.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000104435 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000027500 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Okazaki T, Wang H, Masliah E, Cao M, Johnson SA, Sundsmo M, Saitoh T, Mori N (June 1996). "SCG10, a neuron-specific growth-associated protein in Alzheimer's disease". Neurobiology of Aging. 16 (6): 883–94. doi:10.1016/0197-4580(95)02001-2. PMID 8622778. S2CID 54320124.
  6. Liu Z, Chatterjee TK, Fisher RA (October 2002). "RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6". The Journal of Biological Chemistry. 277 (40): 37832–9. doi:10.1074/jbc.M205908200. PMID 12140291.
  7. "Entrez Gene: STMN2 stathmin-like 2".

Further reading

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