Salicylate decarboxylase
Salicylate decarboxylase (EC 4.1.1.91, salicylic acid decarboxylase, Scd) is an enzyme with systematic name salicylate carboxy-lyase.[1] This enzyme catalyses the following chemical reaction
- salicylate phenol + CO2
| Salicylate decarboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.1.1.91 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
In the reverse direction the enzyme catalyses the regioselective carboxylation of phenol into salicylate.
References
- Kirimura K, Gunji H, Wakayama R, Hattori T, Ishii Y (April 2010). "Enzymatic Kolbe-Schmitt reaction to form salicylic acid from phenol: enzymatic characterization and gene identification of a novel enzyme, Trichosporon moniliiforme salicylic acid decarboxylase". Biochemical and Biophysical Research Communications. 394 (2): 279–84. doi:10.1016/j.bbrc.2010.02.154. PMID 20188702.
External links
- Salicylate+decarboxylase at the US National Library of Medicine Medical Subject Headings (MeSH)
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