Sequence-defined polymer

Sequence-defined polymer (Syn. sequence-specific polymer, sequence-ordered polymer) is a uniform macromolecule with an exact chain-length and a perfectly defined sequence of monomers.[1][2] In other words, each monomer unit is at a defined position in the chain e.g. peptides, proteins, oligonucleotides.[3] Sequence-defined polymers constitute therefore a subclass of the field of sequence-controlled polymers.[1]

References

  1. Lutz, Jean-François; Ouchi, Makoto; Liu, David R.; Sawamoto, Mitsuo (2013-08-09). "Sequence-Controlled Polymers". Science. 341 (6146): 1238149. doi:10.1126/science.1238149. ISSN 0036-8075. PMID 23929982.
  2. Lutz, Jean-François (2017-12-01). "Defining the Field of Sequence-Controlled Polymers". Macromolecular Rapid Communications. 38 (24): n/a. doi:10.1002/marc.201700582. ISSN 1521-3927. PMID 29160615.
  3. Lehto, Taavi; Wagner, Ernst (2014-12-23). "Sequence-defined polymers for the delivery of oligonucleotides". Nanomedicine. 9 (18): 2843–2859. doi:10.2217/nnm.14.166. PMID 25535686.


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