Sh3 and sylf domain containing 1

SH3YL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2D8H
Identifiers
Aliases	SH3YL1, RAY, SH3 and SYLF domain containing 1
External IDs	OMIM: 617314 MGI: 1346118 HomoloGene: 31662 GeneCards: SH3YL1
Gene location (Human)
Chr.	Chromosome 2 (human)[1]
End	266,398 bp[1]
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)[2]
End	30,960,162 bp[2]
Gene ontology
Molecular function	• phosphatase binding; • GO:0001948 protein binding; • phosphatidylinositol binding;
Cellular component	• ruffle membrane;
Biological process	• phosphatidylinositol biosynthetic process; • regulation of ruffle assembly;
	Sources:Amigo / QuickGO
Orthologs
	26751
	24057
	ENSG00000035115
	ENSMUSG00000020669
	Q96HL8
	O08641
	NM_001159597; NM_001282682; NM_001282687; NM_015677
	NM_001289480; NM_013709
	NP_001153069; NP_001269611; NP_001269616; NP_056492
	NP_001276409; NP_038737
	Wikidata
View/Edit Human	View/Edit Mouse

SH3 and SYLF domain containing 1 is a protein that in humans is encoded by the SH3YL1 gene.[5]

References

GRCh38: Ensembl release 89: ENSG00000035115 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000020669 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: SH3 and SYLF domain containing 1".

Asbach B, Ludwig C, Saksela K, Wagner R (2012). "Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome". PLOS ONE. 7 (6): e38540. doi:10.1371/journal.pone.0038540. PMC 3379994. PMID 22745667.
Hasegawa J, Tokuda E, Tenno T, Tsujita K, Sawai H, Hiroaki H, Takenawa T, Itoh T (May 2011). "SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain". The Journal of Cell Biology. 193 (5): 901–16. doi:10.1083/jcb.201012161. PMC 3105542. PMID 21624956.
Aoki N, Ito K, Ito M (May 2000). "A novel mouse gene, Sh3yl1, is expressed in the anagen hair follicle". The Journal of Investigative Dermatology. 114 (5): 1050–6. doi:10.1046/j.1523-1747.2000.00971.x. PMID 10771491.
Shimomura Y, Aoki N, Ito K, Ito M (February 2003). "Gene expression of Sh3d19, a novel adaptor protein with five Src homology 3 domains, in anagen mouse hair follicles". Journal of Dermatological Science. 31 (1): 43–51. doi:10.1016/s0923-1811(02)00140-8. PMID 12615363.

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