Shruti Naik

Shruti Naik is an Indian American scientist who is an Assistant Professor of Biological Sciences at the NYU Langone Medical Center. In 2020 Naik was named a Packard Fellow for her research into the molecular mechanisms that underpin the function of tissue stem cells. She was awarded the 2018 regional Blavatnik Awards for Young Scientists.

Shruti Naik
Alma materUniversity of Pennsylvania
Rockefeller University
University of Maryland, College Park
Scientific career
InstitutionsNYU Langone Medical Center
ThesisHost-commensal cross talk at the cutaneous interface (2012)
Doctoral advisorYasmine Belkaid

Early life and education

Naik was born in India, and moved to America at the age of twelve.[1] Naik dealt with the culture shock through humour, and made her way through high school as a stand-up comedian.[1] Whilst a high school student Naik came across the story of Bonnie Bassler, a biologist at Princeton University, who was working on glowing bacteria.[1] After watching Bassler on television, Naik decided she wanted to become a biologist, and took classes in microbiology at high school.[1] She was an undergraduate student at the University of Maryland, College Park, where she majored in cell and molecular biology.[2] As an undergraduate Naik worked in the Food and Drug Administration laboratory on campus.[1] After graduating, Naik was appointed to the Naval Medical Research Center, where she looked at immune responses to traumatic brain injury.[1] Naik completed her doctoral research at the University of Pennsylvania under the supervision of Yasmine Belkaid.[3] She was a postdoctoral fellow at Rockefeller University.

Research and career

Naik studies the interactions between immune cells and microbes in biological tissue. In particular, Naik is interested in the tissues that interface with various organs, including the skin, lungs and gut.[4] She has investigated inflammation and tissue regeneration, host-microbe interactions and immunity.[4] Her research on skin stem cells was the first to identify how the skin remembers injuries and exposure to irritants, showing that the long-lived epithelial stem cells in the skin have a memory to inflammatory stimuli. Repeated exposure can change the genetic landscape of stem cells, making them quicker to respond when they next encounter an attack. This response can be beneficial, such as allowing for faster healing of wounds, or they can be damaging, such as allowing for inflammatory skin diseases such as psoriasis.[5] Naik was made a Packard Fellow in 2020.[6]

Awards and honours

Selected publications

  • Engwerda, Christian (2012-08-09). "Faculty Opinions recommendation of Compartmentalized control of skin immunity by resident commensals". Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature. doi:10.3410/f.717952313.793458263. Retrieved 2020-10-16.
  • Iida, Noriho; Dzutsev, Amiran; Stewart, C. Andrew; Smith, Loretta; Bouladoux, Nicolas; Weingarten, Rebecca A.; Molina, Daniel A.; Salcedo, Rosalba; Back, Timothy; Cramer, Sarah; Dai, Ren-Ming (2013-11-22). "Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment". Science. 342 (6161): 967–970. Bibcode:2013Sci...342..967I. doi:10.1126/science.1240527. ISSN 0036-8075. PMC 6709532. PMID 24264989.
  • Naik, Shruti; Bouladoux, Nicolas; Linehan, Jonathan L.; Han, Seong-Ji; Harrison, Oliver J.; Wilhelm, Christoph; Conlan, Sean; Himmelfarb, Sarah; Byrd, Allyson L.; Deming, Clayton; Quinones, Mariam (2015). "Commensal–dendritic-cell interaction specifies a unique protective skin immune signature". Nature. 520 (7545): 104–108. Bibcode:2015Natur.520..104N. doi:10.1038/nature14052. ISSN 1476-4687. PMC 4667810. PMID 25539086.

References

  1. Gewin, Virginia (2017). "Turning point: Microbe detective". Nature. 542 (7639): 129. doi:10.1038/nj7639-129a. ISSN 1476-4687.
  2. "2017 Sartorius Prize winners". Science | AAAS. 2018-03-27. Retrieved 2020-10-16.
  3. Naik, Shruti (2012). Host-commensal cross talk at the cutaneous interface (Thesis). OCLC 829426783.
  4. "Shruti Naik". med.nyu.edu. Retrieved 2020-10-16.
  5. "Shruti Naik | Blavatnik Awards for Young Scientists". blavatnikawards.org. Retrieved 2020-10-16.
  6. "2020 Class of Packard Fellows Announced". The David and Lucile Packard Foundation. 2020-10-15. Retrieved 2020-10-16.
  7. Inc, Regeneron Pharmaceuticals. "Regeneron Announces 2015 Winners of the Regeneron Prize for Creative Innovation". www.prnewswire.com. Retrieved 2020-10-16.
  8. "Dr. Shruti Naik: Discovery, Disease, and the Empowerment of Women Scientists". The Scientista Foundation. Retrieved 2020-10-16.
  9. "Nature Research Awards 2018 Longlist". www.nature.com. Retrieved 2020-10-16.
  10. "Dale F. Frey Breakthrough Scientists: Current and Former Awardees". Damon Runyon. Retrieved 2020-10-16.
  11. "2018 Highlights in Faculty Awards". About. Retrieved 2020-10-16.
  12. "2019 Innovators in Science Award Winners Announced | Takeda". www.takeda.com. Retrieved 2020-10-16.
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