Solasodine
Solasodine is a poisonous alkaloid chemical compound that occurs in plants of the family Solanaceae such as potatoes and tomatoes.[1] Solasonine and solamargine are glycoalkaloid derivatives of solasodine.[1] Solasodine is teratogenic to hamster fetuses in a dose of 1200 to 1600 mg/kg.[2] Literature survey reveals that solasodine has diuretic, anticancer, antifungal, cardiotonic, antispermatogenetic, antiandrogenic, immunomodulatory, antipyretic and various effects on central nervous system. [3]
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| IUPAC name
(3β,22α,25R)-Spirosol-5-en-3-ol | |
| Other names
Purapuridine; Solancarpidine; Solanearpidine; Solanidine-S | |
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| ChemSpider | |
| ECHA InfoCard | 100.004.341  |
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| Properties | |
| C27H43NO2 | |
| Molar mass | 413.646 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is  ?) | |
| Infobox references | |
Uses
It is commercially used as a precursor for the production of complex steroidal compounds such as contraceptive pills.[1]
See also
References
- Everist, S.L. (1981). Poisonous Plants of Australia. Angus & Robertson. ISBN 978-0-207-14228-4.
- Kinghorn, A.D. (2010). "Toxins and Teratogens of the Solanaceae and Liliaceae". Toxic plants. Society for Economic Botany, Columbia University Press. pp. 75–76. ISBN 978-0231515689.
- Patel, Kanika; Singh, Ravi B.; Patel, Dinesh K. (2013). "Medicinal significance, pharmacological activities, and analytical aspects of solasodine: A concise report of current scientific literature". Journal of Acute Disease. 2 (2): 92–98. doi:10.1016/S2221-6189(13)60106-7.
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