Spirillum minus

Spirillum minus is an organism associated with rat-bite fever (specifically sodoku)[2][3][4] that has never been fully identified and was assigned to the genus Spirillum in 1887 based on morphology, although it is not a validly published name. As Spirillum species generally obligately microaerophiles and are not found in mammals, this organism may be misclassified. Sequencing data should help to resolve this question.

Spirillum minus
Scientific classification
Domain: Bacteria
Phylum: Proteobacteria
Class: Betaproteobacteria
Order: Nitrosomonadales
Family: Spirillaceae
Genus: Spirillum
Species:
S. minus
Binomial name
Spirillum minus
Carter, 1887[1]

This organism is presumed to be a bacterium. It stains gram-negative and has a coiled rod shape. It does not grow in vitro, and requires inoculation in animals for growth. No attempts to sequence the organism are known as of 2015.[5]

References

  1. Lapson CL (1941). "Rat-Bite Fever in Washington, D. C., Due to Spirillum minus and Streptobacillus moniliformis". Public Health Reports (1896-1970). 56 (40): 1961. doi:10.2307/4583884.
  2. "Spirillum" at Dorland's Medical Dictionary
  3. Gaastra W, Boot R, Ho HT, Lipman LJ (January 2009). "Rat bite fever". Veterinary Microbiology. 133 (3): 211–28. doi:10.1016/j.vetmic.2008.09.079. PMID 19008054.
  4. Dendle C, Woolley IJ, Korman TM (December 2006). "Rat-bite fever septic arthritis: illustrative case and literature review". European Journal of Clinical Microbiology & Infectious Diseases. 25 (12): 791–7. doi:10.1007/s10096-006-0224-x. PMID 17096137.
  5. Washburn RG (2015). "Rat-Bite Fever: Streptobacillus moniliformis and Spirillum minus". Mandell, Douglas, and Bennett's principles and practice of infectious diseases (Eighth ed.). Philadelphia, PA. pp. 2629–2632. doi:10.1016/B978-1-4557-4801-3.00233-2. ISBN 978-1-4557-4801-3.
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