TARS (gene)

Threonyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the TARS gene.[4]

TARS1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTARS1, ThrRS, threonyl-tRNA synthetase, TARS, threonyl-tRNA synthetase 1, TTD7
External IDsOMIM: 187790 MGI: 106314 HomoloGene: 11852 GeneCards: TARS1
Gene location (Human)
Chr.Chromosome 5 (human)[1]
Band5p13.3Start33,440,696 bp[1]
End33,469,539 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

6897

110960

Ensembl

ENSG00000113407

ENSMUSG00000022241

UniProt

P26639

Q9D0R2

RefSeq (mRNA)

NM_001258437
NM_001258438
NM_152295

NM_033074

RefSeq (protein)

NP_001245366
NP_001245367
NP_689508

NP_149065

Location (UCSC)Chr 5: 33.44 – 33.47 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Aminoacyl tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family[4]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000113407 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Entrez Gene: TARS threonyl-tRNA synthetase".

Further reading


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