TMED2

Transmembrane emp24 domain-containing protein 2 is a protein that in humans is encoded by the TMED2 gene.[4][5]

TMED2
Identifiers
AliasesTMED2, P24A, RNP24, p24, p24b1, p24beta1, transmembrane p24 trafficking protein 2
External IDsMGI: 3704329 HomoloGene: 55991 GeneCards: TMED2
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12q24.31Start123,584,533 bp[1]
End123,598,582 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

10959

100862175

Ensembl

ENSG00000086598

n/a

UniProt

Q15363

Q9R0Q3

RefSeq (mRNA)

NM_006815
NM_001321445

XM_003945446

RefSeq (protein)

NP_001308374
NP_006806

NP_062744

Location (UCSC)Chr 12: 123.58 – 123.6 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

TMED2 has been shown to interact with GORASP1[6] and GORASP2.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000086598 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. Blum R, Feick P, Puype M, Vandekerckhove J, Klengel R, Nastainczyk W, Schulz I (July 1996). "Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking". The Journal of Biological Chemistry. 271 (29): 17183–9. doi:10.1074/jbc.271.29.17183. PMID 8663407.
  5. "Entrez Gene: TMED2 transmembrane emp24 domain trafficking protein 2".
  6. Barr FA, Preisinger C, Kopajtich R, Körner R (December 2001). "Golgi matrix proteins interact with p24 cargo receptors and aid their efficient retention in the Golgi apparatus". The Journal of Cell Biology. 155 (6): 885–91. doi:10.1083/jcb.200108102. PMC 2150891. PMID 11739402.

Further reading


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