TNIP2

TNFAIP3-interacting protein 2 is a protein that in humans is encoded by the TNIP2 gene.[5][6][7] TNIP2 contains multiple amino acid sites that are phosphorylated and ubiquitinated.[8]

TNIP2
Identifiers
AliasesTNIP2, ABIN2, FLIP1, KLIP, TNFAIP3 interacting protein 2
External IDsOMIM: 610669 MGI: 2386643 HomoloGene: 11515 GeneCards: TNIP2
Gene location (Human)
Chr.Chromosome 4 (human)[1]
Band4p16.3Start2,741,648 bp[1]
End2,756,342 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

79155

231130

Ensembl

ENSG00000168884

ENSMUSG00000059866

UniProt

Q8NFZ5

Q99JG7

RefSeq (mRNA)

NM_024309
NM_001161527
NM_001292016

NM_139064

RefSeq (protein)

NP_001154999
NP_001278945
NP_077285

NP_620703

Location (UCSC)Chr 4: 2.74 – 2.76 MbChr 5: 34.5 – 34.51 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse



References

  1. GRCh38: Ensembl release 89: ENSG00000168884 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000059866 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Van Huffel S, Delaei F, Heyninck K, De Valck D, Beyaert R (Aug 2001). "Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2". J Biol Chem. 276 (32): 30216–23. doi:10.1074/jbc.M100048200. PMID 11390377.
  6. Tadros A, Hughes DP, Dunmore BJ, Brindle NP (Dec 2003). "ABIN-2 protects endothelial cells from death and has a role in the antiapoptotic effect of angiopoietin-1". Blood. 102 (13): 4407–9. doi:10.1182/blood-2003-05-1602. PMID 12933576.
  7. "Entrez Gene: TNIP2 TNFAIP3 interacting protein 2".
  8. "TNIP2 (human)". www.phosphosite.org. Retrieved 2020-10-31.

Further reading


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