TRIP12

Probable E3 ubiquitin-protein ligase TRIP12 is an enzyme that in humans is encoded by the TRIP12 gene.[4][5]

TRIP12
Identifiers
AliasesTRIP12, TRIP-12, ULF, thyroid hormone receptor interactor 12
External IDsOMIM: 604506 MGI: 1309481 HomoloGene: 44226 GeneCards: TRIP12
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9320

14897

Ensembl

ENSG00000153827

ENSMUSG00000026219

UniProt

Q14669

G5E870

RefSeq (mRNA)

NM_001284214
NM_001284215
NM_001284216
NM_004238

NM_133975

RefSeq (protein)

NP_598736

Location (UCSC)n/aChr 1: 84.72 – 84.84 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

TRIP12 has been shown to interact with APPBP1.[6]

References

  1. GRCm38: Ensembl release 89: ENSMUSG00000026219 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. Lee JW, Choi HS, Gyuris J, Brent R, Moore DD (Jul 1995). "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor". Mol Endocrinol. 9 (2): 243–54. doi:10.1210/me.9.2.243. PMID 7776974.
  5. "Entrez Gene: TRIP12 thyroid hormone receptor interactor 12".
  6. Park, Yoon; Yoon Sungjoo Kim; Yoon Jong-Bok (Sep 2008). "TRIP12 functions as an E3 ubiquitin ligase of APP-BP1". Biochem. Biophys. Res. Commun. United States. 374 (2): 294–8. doi:10.1016/j.bbrc.2008.07.019. PMID 18627766.

Further reading


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