TUBB

Tubulin beta chain is a protein that in humans is encoded by the TUBB gene.[5][6][7]

TUBB
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTUBB, CDCBM6, M40, OK/SW-cl.56, TUBB1, TUBB5, CSCSC1, tubulin beta class I
External IDsOMIM: 191130 MGI: 107812 HomoloGene: 69099 GeneCards: TUBB
Gene location (Human)
Chr.Chromosome 6 (human)[1]
Band6p21.33Start30,720,352 bp[1]
End30,725,426 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

203068

22154

Ensembl

ENSMUSG00000001525

UniProt

P07437
Q5SU16

P99024

RefSeq (mRNA)

NM_011655

RefSeq (protein)

NP_035785

Location (UCSC)Chr 6: 30.72 – 30.73 MbChr 17: 35.83 – 35.84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

TUBB has been shown to interact with NCOA6[8] and SYT9.[9]

See also

References

  1. ENSG00000232421, ENSG00000183311, ENSG00000224156, ENSG00000235067, ENSG00000232575, ENSG00000227739, ENSG00000229684 GRCh38: Ensembl release 89: ENSG00000196230, ENSG00000232421, ENSG00000183311, ENSG00000224156, ENSG00000235067, ENSG00000232575, ENSG00000227739, ENSG00000229684 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000001525 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Crabtree DV, Ojima I, Geng X, Adler AJ (Aug 2001). "Tubulins in the primate retina: evidence that xanthophylls may be endogenous ligands for the paclitaxel-binding site". Bioorganic & Medicinal Chemistry. 9 (8): 1967–76. doi:10.1016/S0968-0896(01)00103-1. PMID 11504633.
  6. Volz A, Weiss E, Trowsdale J, Ziegler A (Jan 1994). "Presence of an expressed beta-tubulin gene (TUBB) in the HLA class I region may provide the genetic basis for HLA-linked microtubule dysfunction". Human Genetics. 93 (1): 42–6. doi:10.1007/BF00218911. PMID 8270253. S2CID 7853030.
  7. "Entrez Gene: TUBB tubulin, beta".
  8. Goo YH, Sohn YC, Kim DH, Kim SW, Kang MJ, Jung DJ, Kwak E, Barlev NA, Berger SL, Chow VT, Roeder RG, Azorsa DO, Meltzer PS, Suh PG, Song EJ, Lee KJ, Lee YC, Lee JW (Jan 2003). "Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins". Molecular and Cellular Biology. 23 (1): 140–9. doi:10.1128/MCB.23.1.140-149.2003. PMC 140670. PMID 12482968.
  9. Haberman Y, Grimberg E, Fukuda M, Sagi-Eisenberg R (Nov 2003). "Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules". Journal of Cell Science. 116 (Pt 21): 4307–18. doi:10.1242/jcs.00719. PMID 12966166.

Further reading


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