TUSC2

Tumor suppressor candidate 2 is a protein that in humans is encoded by the TUSC2 gene.[5][6][7]

TUSC2
Identifiers
AliasesTUSC2, C3orf11, FUS1, PAP, PDAP2, tumor suppressor candidate 2, tumor suppressor 2, mitochondrial calcium regulator
External IDsOMIM: 607052 MGI: 1931086 HomoloGene: 5264 GeneCards: TUSC2
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3p21.31Start50,320,027 bp[1]
End50,328,251 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

11334

80385

Ensembl

ENSG00000114383

ENSMUSG00000010054

UniProt

O75896

Q9WVF8

RefSeq (mRNA)

NM_007275

NM_019742

RefSeq (protein)

NP_009206

NP_062716

Location (UCSC)Chr 3: 50.32 – 50.33 MbChr 9: 107.56 – 107.57 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000114383 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000010054 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Fischer WH, Schubert D (Jan 1997). "Characterization of a novel platelet-derived growth factor-associated protein". J Neurochem. 66 (5): 2213–6. doi:10.1046/j.1471-4159.1996.66052213.x. PMID 8780057. S2CID 28782367.
  6. Kondo M, Ji L, Kamibayashi C, Tomizawa Y, Randle D, Sekido Y, Yokota J, Kashuba V, Zabarovsky E, Kuzmin I, Lerman M, Roth J, Minna JD (Oct 2001). "Overexpression of candidate tumor suppressor gene FUS1 isolated from the 3p21.3 homozygous deletion region leads to G1 arrest and growth inhibition of lung cancer cells". Oncogene. 20 (43): 6258–62. doi:10.1038/sj.onc.1204832. PMID 11593436.
  7. "Entrez Gene: TUSC2 tumor suppressor candidate 2".

Further reading


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