The Research Institute at Nationwide Children's Hospital

The Research Institute at Nationwide Children's Hospital is one of America's ten largest free-standing pediatric research centers and works to enhance the health of children by engaging in research.

The Research Institute at Nationwide Children's Hospital
Nationwide Children's Hospital
Geography
LocationNationwide Children's Hospital, Columbus, Ohio, United States
Coordinates39.95242°N 82.979428°W / 39.95242; -82.979428
Links
WebsiteThe Research Institute at Nationwide Children's Hospital
ListsHospitals in Ohio

History

Origins

Research at the Children's Hospital can be traced back to the founding in 1892. Following World War II, extensive resources were dedicated to research, which led to the first successful treatment of histoplasmosis by Dr. Warren Wheeler. Eventually the research conducted at the hospital would be consolidated under C-H-I-L-D, or Children’s Hospital Investigative Laboratory Division. In 1964, Children’s Hospital Research Foundation was founded. In 1998, The Children's Hospital Research Foundation became the Columbus Children's Research Institute. In 2007, following a gift from the Nationwide Foundation, it became The Research Institute at Nationwide Children's Hospital.[1]

Medical firsts, breakthroughs, and contributions

The first successful treatment of histoplasmosis by Dr. Warren Wheeler occurred at the center in the mid-20th century. In 1965, the world's first rhinovirus reference center was established in Ross Hall at the Hospital. In the 1970s, research by the hospital contributed to an innovative therapy in the fight against Reye's Syndrome. In the 1980s, Dr. Samuel Mites created microvolume techniques for bloodwork and Dr. H. William Chatworthy pioneered pediatric surgeries by developing portosystemic shunt procedures. In the 1990s, Dr. Christopher Walker led a nationwide project on hepatitis C infection and immunobiology. In 2000, Dr. Robert Castile patented breakthrough technology, an "adult-type" infant pulmonary function testing device. In 2003, the research institute conducted HIV vaccine trials. In 2006, the first human gene therapy trial for muscular dystrophy was conducted at the research institute. In 2009, the institute again conducted trials for an HIV vaccine.[2]

2019 Rededication

In early 2019, the center was rededicated the Abigail Wexner Research Institute at Nationwide Children's Hospital, with corresponding new signage on all buildings.

Espionage

In August 2020 Li Chen pled guilty to stealing trade secrets and other intellectual property from the Research Institute at Nationwide Children's Hospital lab where she and her husband worked for ten years. Most of the stollen information related to exosomes and their therapeutic use. In return for bringing the technology to China she received benefits from the State Administration of Foreign Expert Affairs, National Natural Science Foundation of China, and multiple government talent acquisition plans.[3]

Research Centers

The Research Institute at Nationwide Children's Hospital is divided into 12 Centers of Emphasis.[4]

References

  1. History of Research Institute, Nationwide Children's Hospital, Retrieved 18 sept 2009.
  2. Research Institute History, Nationwide Children's Hospital, Retrieved 18 sept 2009.
  3. Girard, Bonnie. "Chinese Government-Paid Scientists Plead Guilty to Stealing Research From an American Children's Hospital". thediplomat.com. The Diplomat. Retrieved 8 August 2020.
  4. Research Institute at Nationwide Children's Hospital Organization, Nationwide Children's Hospital, Retrieved 18 sept 2009.
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