Turnip crinkle virus (TCV) repressor of minus strand synthesis H5

The TCV hairpin 5 (H5) is an RNA element found in the turnip crinkle virus. This RNA element is composed of a stem-loop that contains a large symmetrical internal loop (LSL). H5 can repress minus-strand synthesis when the 3' side of the LSL pairs with the 4 bases at the 3'-terminus of the RNA(GCCC-OH).[1][2]

Turnip crinkle virus (TCV) repressor of minus strand synthesis H5
Identifiers
SymbolTCV_H5
RfamRF00500
Other data
RNA typeCis-reg
Domain(s)Viruses
SOSO:0000233
PDB structuresPDBe

See also

References

  1. McCormack JC, Simon AE (July 2004). "Biased hypermutagenesis associated with mutations in an untranslated hairpin of an RNA virus". Journal of Virology. 78 (14): 7813–7817. doi:10.1128/JVI.78.14.7813-7817.2004. PMC 434097. PMID 15220455.
  2. Zhang G, Zhang J, Simon AE (July 2004). "Repression and derepression of minus-strand synthesis in a plus-strand RNA virus replicon". Journal of Virology. 78 (14): 7619–7633. doi:10.1128/JVI.78.14.7619-7633.2004. PMC 434078. PMID 15220437.
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