UBP1

UBP1
Identifiers
Aliases	UBP1, LBP-1B, LBP-1a, LBP1A, LBP1B, upstream binding protein 1 (LBP-1a), upstream binding protein 1
External IDs	OMIM: 609784 MGI: 104889 HomoloGene: 8435 GeneCards: UBP1
Gene location (Human)
Chr.	Chromosome 3 (human)[1]
End	33,441,371 bp[1]
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)[2]
End	113,977,202 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• DNA binding; • GO:0001106 transcription corepressor activity; • sequence-specific DNA binding; • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	• cell nucleus; • nucleoplasm; • cytosol;
Biological process	• viral replication; • negative regulation of transcription, DNA-templated; • regulation of transcription, DNA-templated; • angiogenesis; • transcription, DNA-templated; • regulation of transcription from RNA polymerase II promoter;
	Sources:Amigo / QuickGO
Orthologs
	7342
	22221
	ENSG00000153560
	ENSMUSG00000009741
	Q9NZI7
	Q811S7
	NM_001128160; NM_001128161; NM_014517
NM_001083319; NM_013699; NM_001372507; NM_001372508; NM_001372510;
	NM_001372511; NM_001372512; NM_001372514
	NP_001121632; NP_001121633; NP_055332
NP_001076788; NP_038727; NP_001359436; NP_001359437; NP_001359439;
	NP_001359440; NP_001359441; NP_001359443
	Wikidata
View/Edit Human	View/Edit Mouse

Upstream-binding protein 1 is a protein that in humans is encoded by the UBP1 gene.[5][6]

References

GRCh38: Ensembl release 89: ENSG00000153560 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000009741 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Yoon JB, Li G, Roeder RG (Mar 1994). "Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro". Mol Cell Biol. 14 (3): 1776–85. doi:10.1128/mcb.14.3.1776. PMC 358535. PMID 8114710.
"Entrez Gene: UBP1 upstream binding protein 1 (LBP-1a)".

Kato H, Horikoshi M, Roeder RG (1991). "Repression of HIV-1 transcription by a cellular protein". Science. 251 (5000): 1476–9. doi:10.1126/science.2006421. PMID 2006421.
Parada CA, Yoon JB, Roeder RG (1995). "A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro". J. Biol. Chem. 270 (5): 2274–83. doi:10.1074/jbc.270.5.2274. PMID 7836461.
Huang N, Miller WL (2000). "Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc". J. Biol. Chem. 275 (4): 2852–8. doi:10.1074/jbc.275.4.2852. PMID 10644752.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Zhao H, Li J, Jiang L (2004). "Inhibition of HIV-1 TAR RNA-Tat peptide complexation using poly(acrylic acid)". Biochem. Biophys. Res. Commun. 320 (1): 95–9. doi:10.1016/j.bbrc.2004.05.148. PMID 15207707.
Huang N, Miller WL (2005). "LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells". Mol. Endocrinol. 19 (2): 409–20. doi:10.1210/me.2004-0086. PMID 15471945.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000153560 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000009741 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8114710-5] Yoon JB, Li G, Roeder RG (Mar 1994). "Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro". Mol Cell Biol. 14 (3): 1776–85. doi:10.1128/mcb.14.3.1776. PMC 358535. PMID 8114710.

[entrez-6] "Entrez Gene: UBP1 upstream binding protein 1 (LBP-1a)".

UBP1

References

Further reading